Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.
Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Martina Lukasova,et al. Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. J Clin Invest. 2011 Mar 1; 121(3): 1163–1173. Published online 2011 Feb 7. doi: 10.1172/JCI41651.
[2] Linlin Ma,et al. Nicotinic Acid Activates the Capsaicin Receptor TRPV1 – A Potential Mechanism for Cutaneous Flushing. Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2015 Jun 1.Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Jun; 34(6): 1272–1280. Published online 2014 Mar 27. doi: 10.1161/ATVBAHA.113.303346.
分子式 C6H5NO2 |
分子量 123.11 |
CAS号 59-67-6 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 30 mg/mL |
Water 2 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
相关化合物库
使用AMQUAR产品发表文献后请联系我们