Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Daniela Mokra, Juraj Mokry. Glucocorticoids in the treatment of neonatal meconium aspiration syndrome. Eur J Pediatr. 2011 Dec; 170(12): 1495–1505. Published online 2011 Apr 6. doi: 10.1007/s00431-011-1453-2.
[2] Marcelo E. Katz,et al. Disruption of Transitional Stages in 24-h Blood Pressure Recording in Renal Transplant Recipients. Front Neurol. 2012; 3: 35. Published online 2012 Mar 16. doi: 10.3389/fneur.2012.00035.
分子式 C22H28O5 |
分子量 372.455 |
CAS号 1247-42-3 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 75 mg/mL |
Water <1 mg/mL |
Ethanol 4 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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