Sulfapyridine is an antibiotic and is mostly used in treating rheumatoid arthritis.
Sulfapyridine is an antibiotic and is mostly used in treating rheumatoid arthritis.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Susanne Liptay,et al. Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine. Br J Pharmacol. 1999 Dec; 128(7): 1361–1369. doi: 10.1038/sj.bjp.0702937.
[2] Susanne Liptay,et al.Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine. Br J Pharmacol. 1999 Dec; 128(7): 1361–1369. doi: 10.1038/sj.bjp.0702937.
[3] C Wahl, S Liptay, et al. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J Clin Invest. 1998 Mar 1; 101(5): 1163–1174. doi: 10.1172/JCI992.
分子式 C11H11N3O2S |
分子量 249.29 |
CAS号 144-83-2 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 2 mg/mL warmed |
Water <1 mg/mL |
Ethanol <1 mg/mL |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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