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Aztreonam

Aztreonam is a synthetic monocyclic beta-lactam antibiotic, which is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. Aztreonam has a very high affinity for penicillin-binding protein 3 (PBP-3).

目录号
EY2249
EY2249
EY2249
EY2249

纯度
98.82%
98.82%
98.82%
98.82%

规格
50 mg
100 mg
200 mg
500 mg

原价
429
790
1120
2350

售价
429
790
1120
2350

库存
现货
现货
现货
现货

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订购
订购
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生物活性

Aztreonam is a synthetic monocyclic beta-lactam antibiotic, which is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. Aztreonam has a very high affinity for penicillin-binding protein 3 (PBP-3).
体外研究
体内研究
激酶实验
细胞实验
动物实验
不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数

例如，已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法：将88 mg/kg 乘以小鼠的Km系数（3），再除以大鼠的Km系数（6），得到该药物用于大鼠的等效剂量44 mg/kg。

参考文献

[1] Douglas J. Biedenbach,et al. In Vitro Activity of Aztreonam-Avibactam against a Global Collection of Gram-Negative Pathogens from 2012 and 2013. Antimicrob Agents Chemother. 2015 Jul; 59(7): 4239–4248. Prepublished online 2015 May 11. Published online 2015 Jun 12. doi: 10.1128/AAC.00206-15.
[2] Qianru Yu,et al. In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells. J Antimicrob Chemother. 2012 Nov; 67(11): 2673–2681. Published online 2012 Jul 26. doi: 10.1093/jac/dks296.

分子式 C13H17N5O8S2	分子量 435.43	CAS号 78110-38-0	储存方式 -20 ℃长期冷藏储存。冰袋运输
溶剂（常温）	DMSO 90 mg/mL	Water 12 mg/mL	Ethanol <1 mg/mL

体内溶解度

Clinical Trial Information ( data from http://clinicaltrials.gov )

注：以上所有数据均来自公开文献，并不保证对所有实验均有效，数据仅供参考。
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Aztreonam

生物活性

体外研究

体内研究

激酶实验

细胞实验

动物实验

不同实验动物依据体表面积的等效剂量转换表（数据来源于FDA指南）

参考文献

Clinical Trial Information ( data from http://clinicaltrials.gov )

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