Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation.
Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation.
动物 A (mg/kg) = 动物 B (mg/kg)×动物 B的Km系数/动物 A的Km系数 | |
例如,已知某工具药用于小鼠的剂量为88 mg/kg , 则用于大鼠的剂量换算方法:将88 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到该药物用于大鼠的等效剂量44 mg/kg。
[1] Ayse Baysal et. Al. Levosimendan improves renal outcome in cardiac surgery: a randomized trial. Journal of Cardiothoracic and Vascular Anesthesia, 28(3), 586-594 (2014).
[2] B Chenuel et. Al. Effects of infusion of human methemoglobin solution following hydrogen sulfide poisoning. Clinical Toxicology, 53(2), 93-101 (2015).
[3] Andreas Alexandrou et. Al. Bsm1 vitamin D receptor polymorphism and calcium homeostasis following bariatric surgery. Journal of Investigative Surgery, 28(1), 8-17 (2015).
分子式 C32H53BrN2O4 |
分子量 609.68 |
CAS号 119302-91-9 |
储存方式 -20 ℃长期冷藏储存。冰袋运输 |
溶剂(常温) |
DMSO 200 mM |
Water 200 mM |
Ethanol 200 mM |
体内溶解度
注:以上所有数据均来自公开文献,并不保证对所有实验均有效,数据仅供参考。
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