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Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid with IC50 of 320 μM.
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Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is a synthetic antimycotic drug with IC50 of 0.93 μM in C. albicans.
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Amorolfine HCl is a antifungal reagent.
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Aztreonam is a synthetic monocyclic beta-lactam antibiotic, which is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. Aztreonam has a very high affinity for penicillin-binding protein 3 (PBP-3).
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Norfloxacin is a broad-spectrum antibiotic which is a fluorinated quinolone Pefloxacin derivative.Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).
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