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  • PF-04217903 EY0999

    PF-04217903是ATP竞争性c-Met抑制剂，IC50为4.8 nM，对突变型Y1230C无活性。

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  • SB590885 EY1002

    SB590885是B-Raf的抑制剂，Ki为0.16 nM，对其它人类激酶无活性。

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  • Rucaparib phosphate EY0972

    Rucaparib phosphate是PARP抑制剂，对PARP1的Ki为1.4 nM，对PARP其余亚型也有亲和性。

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  • SU11274 EY0974

    SU11274(PKI-SU11274)是Met抑制剂，IC50为10 nM，对PGDFRβ，EGFR和Tie2无活性。

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  • GSK J4 HCl EY0977

    GSK J4 hydrochloride is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM and inactive against a panel of demethylases of the JMJ family.

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