Home > 暂无记录 Signal Pathway > NF-κB

NF-κB


NF-κB is important in regulating cellular responses because it belongs to the category of "rapid-acting" primary transcription factors, i.e., transcription factors that are present in cells in an inactive state and do not require new protein synthesis in order to become activated (other members of this family include transcription factors such as c-Jun, STATs, and nuclear hormone receptors). This allows NF-κB to be a first responder to harmful cellular stimuli. Known inducers of NF-κB activity are highly variable and include reactive oxygen species (ROS), tumor necrosis factor alpha (TNFα), interleukin 1-beta (IL-1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaine, and ionizing radiation.

  • Oxymetazoline hydrochloride EY2385

    Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist.

    More

  • Cisatracurium Besylate EY2362

    Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

    More

  • Betaxolol EY2357

    Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.

    More

  • Terazosin HCl EY2344

    Hytrin (terazosin) is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.

    More

  • Phentolamine Mesylate EY2340

    Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.

    More

  • Oxymetazoline hydrochloride EY2385

    Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist.

    More

  • Cisatracurium Besylate EY2362

    Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

    More

  • Betaxolol EY2357

    Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.

    More

  • Terazosin HCl EY2344

    Hytrin (terazosin) is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.

    More

  • Phentolamine Mesylate EY2340

    Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.

    More
    • Current page6, Total Pages29, Total Record141 First Prev 45678 Next Last Goto
More