Home > 暂无记录 Signal Pathway > MAPK

MAPK


MAPK(A mitogen-activated protein kinase)  is a type of protein kinase that is specific to the amino acids serine, threonine, and tyrosine . MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis.

  • 20(S)-Hydroxycholesterol EI0233

    20(S)-Hydroxycholesterol是Hedgehog (Hh) signaling 的变构的激动剂， induces Smo(Smoothened) accumulation。

    More

  • BI-847325 EY2849

    BI-847325是一种口服具有生物活性的选择性的双重MEK/Aurora kinase抑制剂，对人类MEK2和AK-C的IC50值分别为4和15 nM。

    More

  • SMANT hydrochloride EI2572

    SMANT hydrochloride是SMANT hydrochloride可以抑制Smoothened (Smo) accumulation。

    More

  • SAG EI2439

    SAG是活性的Smoothened receptor的激动剂，可以激活Hedgehog信号通路。

    More

  • Quinine hydrochloride EI2291

    Quinine hydrochloride是抗疟活性。

    More
    • Current page2, Total Pages5, Total Record21 First Prev 12345 Next Last Goto
More