MAPK(A mitogen-activated protein kinase) is a type of protein kinase that is specific to the amino acids serine, threonine, and tyrosine . MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis.
Ergothioneine is an imidazole-2-thione derivative with orally active histidine betaine. Ergothioneine is a specific inhibitor of p38-MAPK and Akt, which plays a protective role in cell apoptosis induced by stress. Ergothioneine has antioxidant activity
MoreMefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
MoreArtemether is an antimalarial for the treatment of resistant strains of falciparum malaria.
MoreGSA 10是Smo(Smoothened) 受体激动剂。
MoreGedunin是Hsp90 抑制剂, 展现抗肿瘤抗疟活性。。
More