CCT 007093是PPM1D抑制剂,能选择性地降低人肿瘤细胞株活力。
MoreRivastigmine tartrate (酒石酸卡巴拉汀) 是胆碱酯酶抑制剂,IC50为5.5 uM,还能抑制丁酰胆碱酯酶和乙酰胆碱酯酶。
MorePHT-427是作用于Akt和PDPK1的双重抑制剂,Akt和PDPK1的PH结构域具有高度亲和力,Ki分别为2.7 μM和5.2 μM。
MoreLaetrile is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.Amygdalin isolated from S. Persicae extract in ISF-1 through a bioactivity-guided fractionation procedure induced the expression of follistatin in HepG2 and C2C12 cell lines.The amygdalin induced increase in TCCSUP migratory behavior indicates that any anti-tumor benefits from amygdalin (seen with the other two cell lines) may depend upon the cancer cell type.Amygdalin is a natural product that owns antitumor activity, less side effects, widely sourced and relatively low priced.
MoreZafirlukast (扎鲁司特) 是口服活性的白三烯受体拮抗剂(LTRA)。
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