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Other Singal pathway


  • TH-302 EY2425

    TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.

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  • Cobicistat EY2427

    Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.

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  • Carbazochrome sodium sulfonate EY2428

    Carbazochrome is an antihemorrhagic for use in the treatment of hemorrhoids.

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  • Tolvaptan EY2414

    Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation.

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  • Acemetacin EY2417

    Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

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