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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Harmane EI1282

    Harmane是Putative endogenous imidazoline ligand. 也是MAO抑制剂。

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  • H 1152 dihydrochloride EI1274

    H 1152 dihydrochloride是选择性 Rho-kinase (ROCK) 抑制剂。

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  • H2L 5765834 EI1275

    H2L 5765834是LPA1，3，5 拮抗剂。

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  • H2L5186303 EI1276

    H2L5186303是活性的，选择性 LPA2 受体拮抗剂。

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  • Guvacine hydrochloride EI1259

    Guvacine hydrochloride是特异性 GABA uptake inhibitor（摄取抑制剂）。

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