In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
HMR 1556是活性选择性 Iks 通道阻断剂。
MoreHA 1100 hydrochloride是细胞膜通透性的选择性 Rho-kinase (ROCK) 抑制剂。
MoreHarmane是Putative endogenous imidazoline ligand. 也是MAO抑制剂。
MoreH 1152 dihydrochloride是选择性 Rho-kinase (ROCK) 抑制剂。
MoreH2L 5765834是LPA1,3,5 拮抗剂。
More