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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Ibudilast是PDE 抑制剂 (非选择性)。

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  • Homoquinolinic acid EI1303

    Homoquinolinic acid是选择性， 活性的 NMDA 激动剂。

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  • HQL 79 EI1305

    HQL 79是人 hematopoietic prostaglandin D synthase (H-PGDS) 抑制剂。

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  • HTMT dimaleate EI1308

    HTMT dimaleate是H1 / H2激动剂。

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  • HU 211 EI1310

    HU 211是NMDA 受体拮抗剂， 也是NF-κB 抑制剂。

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