In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
HQL 79是人 hematopoietic prostaglandin D synthase (H-PGDS) 抑制剂。
MoreHTMT dimaleate是H1 / H2激动剂。
MoreHU 211是NMDA 受体拮抗剂, 也是NF-κB 抑制剂。
MoreHerbimycin A是Src 家族激酶抑制剂。也是Hsp90 抑制剂。
MoreHKI 357是ErbB2和EGFR双重不可逆的抑制剂。
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