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GW788388, a potent, selective, and orally active inhibitor of TGFβ signaling, shows potent anti-fibrosis effect. GW788388是一种有效的，选择性的ALK5抑制剂，IC50为18 nM，也抑制其他TGF-βI型和II型受体激酶活性，但不抑制BMP II型受体。
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Ricolinostat (ACY-1215) is an oral, first-in-class, selective inhibitor of HDAC6, and inhibits tubulin deacetylase. Rocilinostat (ACY-1215)是高效HDAC6抑制剂，IC50为5 nM，比对HDAC1/2/3的抑制性高10倍以上，对HDAC8有微弱活性，对HDAC4/5/7/9/11，Sirtuin1和Sirtuin2活性最低。
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Bisindolylmaleimide I (BMI, GF109203X) is a high selectivity, cell-permeable and ATP-competitive inhibitor of PKC and shows GSK-3 inhibition as well. GF 109203X是一种有效的PKC抑制剂，抑制PKCα，PKCβI，PKCβII和PKCγ，IC50分别为20 nM，17 nM，16nM和20 nM，作用于PKC比作用于EGFR，PDGFR和胰岛素受体选择性高3000倍以上。
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StemRegenin 1 (SR1), a purine derivative, is a high affinity antagonist of the aryl hydrocarbon receptor (AhR) transcription factor that expands CD34+ cells. StemRegenin 1(SR1)是芳香烃受体（AhR）拮抗剂，能促进人CD34+外周血和脐带血造血干细胞（HSC）的自我更新。
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Nicotinamide (NAM), an amide form of niacin (vitamin B3), is a water-soluble and noncompetitive inhibitor of the deacetylation reaction catalyzed by Sirtuins and it acts as constituent of the enzyme cofactors NAD and NADP. Nicotinamide (Vitamin B3) 是一种水溶性维生素，是NAD 和 NADP的活性成分，也是一种sirtuins抑制剂。
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