U0126 是一种有效,非 ATP 竞争性的,选择性的 MEK1 和 MEK2 抑制剂,IC50 分别为 72 nM 和 58 nM。U0126 是一种自噬 (autophagy) 和线粒体自噬 (mitophagy) 抑制剂.
MorePyridone 6是一种泛JAK抑制剂,对JAK2, TYK2, JAK3和JAK1的IC50分别为1nM,1nM,5 nM和15 nM
MorePtdIns (4)-P1-fluorescein (ammonium salt) is a fluorescent derivative of phosphatidylinositol
MoreClozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di.
MoreErgothioneine is an imidazole-2-thione derivative with orally active histidine betaine. Ergothioneine is a specific inhibitor of p38-MAPK and Akt, which plays a protective role in cell apoptosis induced by stress. Ergothioneine has antioxidant activity
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