Eculizumab, a humanized anti-complement C5 monoclonal antibody for treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome, blocks the terminal complement pathway required for serum bactericidal activity (SBA).
MoreAtezolizumab (MPDL3280A), a monoclonal antibody that binds to PD-L1 and blocks its interaction with PD-1, was approved for the treatment of platinum-resistant metastatic non-small cell lung cancer (NSCLC) and cisplatin-resistant bladder cancer.
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