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  • KPT-185 EY1798

    KPT-185 is an orally bioavailable selective inhibitor of CRM1 amd displayes potent antiproliferative properties at submicromolar concentrations (IC50 values:100-500nM), induced apoptosis (average 5-fold increase), cell-cycle arrest, and myeloid differentiation in AML cell lines and patient blasts.

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  • ASP3026 EY1799

    ASP3026是高活性ALK抑制剂，IC50为3.5 nM。

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  • AT101 EY1786

    AT101乙酸盐对Bcl-2， Bcl-xL和Mcl-1的结合Ki值分别为0.32，0.48和0.18uM。

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  • Iloperidone EY1771

    Iloperidone是D2/5-HT2受体拮抗剂，可作用于精神分裂症。

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  • INO-1001 EY1772

    INO-1001是PARP抑制剂，IC50为3 nM。

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