Oct-4


Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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    Chlorprothixene与多巴胺和组织胺受体(如D1, D2, D3, D5, H1, 5-HT2, 5-HT6和5-HT7)具有强结合力, Ki值分别为18nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM和5.6 nM。

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    MetoclopraMide hydrochloride is a selective dopamine D2 receptor antagonist which is used for the treatment of nausea and vomiting.

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    L-DOPA是DOPA的天然形式,是多巴胺前体,可作用于帕金森氏病。

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    All-trans retinoic acid可作用于前列腺癌等众多癌症。

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    Adapalene (阿达帕林; CD-271; Differin) 是合成的维甲酸,为维甲酸受体(RAR)激动剂。

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  • Chlorprothixene EY1811

    Chlorprothixene与多巴胺和组织胺受体(如D1, D2, D3, D5, H1, 5-HT2, 5-HT6和5-HT7)具有强结合力, Ki值分别为18nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM和5.6 nM。

    More
  • Metoclopramide HCl EY1736

    MetoclopraMide hydrochloride is a selective dopamine D2 receptor antagonist which is used for the treatment of nausea and vomiting.

    More
  • Levodopa EY1677

    L-DOPA是DOPA的天然形式,是多巴胺前体,可作用于帕金森氏病。

    More
  • Tretinoin ATRA EY1656

    All-trans retinoic acid可作用于前列腺癌等众多癌症。

    More
  • Adapalene EY1512

    Adapalene (阿达帕林; CD-271; Differin) 是合成的维甲酸,为维甲酸受体(RAR)激动剂。

    More
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