NBC
The sodium bicarbonate cotransporter (NBC) family is a part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein.
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GSK3787 is a selective and irreversible PPARβ/δ antagonist with good pharmacokinetic properties. GSK3787是不可逆的PPARδ选择性拮抗剂，pIC50为6.6，对hPPARα和hPPARγ无亲和力。
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Ketoprofen is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.
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Carprofen reduces inflammation by inhibition of COX-2 and other sources of inflammatory prostaglandins, does not interfere with COX-1 activity.
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NS-398是一种COX-2抑制剂，抑制作用呈浓度依赖性。100μM NS-398不影响COX-1活性， 而抑制COX-2活性（IC50: 3.8 μM）。
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Bufexamac是COX环氧酶抑制剂，靶点是IFN-α， EC50 为8.9 μM, 具有抗炎活性。
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