EAATs(Glutamate transporters)
EAATs (Glutamate transporters, Excitatory amino-acid transporters,SLC1, GLT-1), being the most abundant subtype of glutamate transporter in the CNS, is a protein thatplays a key role in regulation of glutamate neurotransmission. and are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia), EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).
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Fluorouracil (5-Fluoracil, 5-FU)是DNA/RNA合成抑制剂，通过抑制胸苷酸合成酶（TS）而干扰核苷酸合成。
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Fludarabine, a purine analog, is used in the treatment of hematological malignancies for the inhibition of STAT-1 activation and DNA synthesis. Fludarabine是一种STAT1活性抑制剂和DNA合成抑制剂。
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CRT0044876 是一种高度选择性APE1抑制剂，其IC50 约为3μM。
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Nedaplatin是顺铂衍生物和DNA损伤剂。
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PSI-7977是核苷酸类似物，可用于慢性HCV感染。
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