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Dehydrogenase


Dehydrogenase is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by a reduction reaction that removes one or more hydrogens from a substrate to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.

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    Teriflunomide是Leflunomide的活性代谢物，通过抑制酶二氢乳清酸脱氢酶，从而抑制嘧啶从头合成，作为一种免疫调节剂。

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  • Leflunomide EY0839

    Leflunomide是抗风湿化合物，是嘧啶合成抑制剂。

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    Trilostane (曲洛司坦; Win 24540; Modrastane) 是3 β-羟化类固醇脱氢酶抑制剂，可作用于库兴氏综合症。

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  • Mycophenolate Mofetil EY0600

    Mycophenolate Mofetil是一种非竞争性的，选择性的，可逆的inosine monophosphate dehydrogenase I/II（次黄嘌呤核苷磷酸脱氢酶I/II）抑制剂， IC50分别为39 nM和27 nM。

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  • PluriSIn 1 EY0350

    PluriSln 1是硬脂酰辅酶A脱氢酶(SCD1）抑制剂。

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