In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
GSK 137647是活性选择性 FFA4 (GPR120) 激动剂。
MoreGSK 269962是活性选择性 ROCK 抑制剂。
MoreGR 135531是高亲和性 melatonin MT3 配体。
MoreGR 89696 fumarate是亚型选择性 κ 激动剂。
MoreGRI 977143是选择性 LPA2 受体 非lipid 激动剂。
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