In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Lincomycin hydrochloride(Lincocin) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
MoreMoroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.
MoreSotalol (Betapace) is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM
MoreBethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.
MoreTolbutamide is an inhibitor of cAMP with IC50 of 4 mM.
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