Home > Signal Pathway > Neuronal Signalling > Dopamine Receptor

Dopamine Receptor


Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors.  There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family. 
  • Chlorprothixene EY1811

    Chlorprothixene与多巴胺和组织胺受体(如D1, D2, D3, D5, H1, 5-HT2, 5-HT6和5-HT7)具有强结合力, Ki值分别为18nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM和5.6 nM。

    More
  • Metoclopramide HCl EY1736

    MetoclopraMide hydrochloride is a selective dopamine D2 receptor antagonist which is used for the treatment of nausea and vomiting.

    More
  • Levodopa EY1677

    L-DOPA是DOPA的天然形式,是多巴胺前体,可作用于帕金森氏病。

    More
  • Dopamine HCl EY1491

    Dopamine hydrochloride 是多巴胺D1-5受体激动剂,是广泛存在于多种动物中的儿茶酚胺神经递质。

    More
  • Paliperidone EY1459

    Paliperidone是多巴胺受体抑拮抗剂。

    More
  • Chlorprothixene EY1811

    Chlorprothixene与多巴胺和组织胺受体(如D1, D2, D3, D5, H1, 5-HT2, 5-HT6和5-HT7)具有强结合力, Ki值分别为18nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM和5.6 nM。

    More
  • Metoclopramide HCl EY1736

    MetoclopraMide hydrochloride is a selective dopamine D2 receptor antagonist which is used for the treatment of nausea and vomiting.

    More
  • Levodopa EY1677

    L-DOPA是DOPA的天然形式,是多巴胺前体,可作用于帕金森氏病。

    More
  • Dopamine HCl EY1491

    Dopamine hydrochloride 是多巴胺D1-5受体激动剂,是广泛存在于多种动物中的儿茶酚胺神经递质。

    More
  • Paliperidone EY1459

    Paliperidone是多巴胺受体抑拮抗剂。

    More
  • Current page18, Total Pages20, Total Record98 First Prev 1617181920 Next Last Goto