Glucocorticoid Receptor
The glucocorticoid receptor (GR,GCR,NR3C1) is the receptor to which cortisol and other glucocorticoids bind.The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. The GR is abnormal in familial glucocorticoid resistance.
In central nervous system structures, the glucocorticoid receptor is gaining interest as a novel representative of neuroendocrine integration, functioning as a major component of endocrine influence - specifically the stress response - upon the brain.
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Hydrocortisone (氢化可的松) 为主要的糖皮质素，由肾上腺皮质分泌。
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Dexamethasone (DEX), a synthetic glucocorticoid, is widely used in clinical settings for its anti-inflammatory effect. Dexamethasone (DHAP)是一种抗炎剂和免疫抑制剂。
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Prednisolone是糖皮质素。
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NMS-1286937是选择性的口服生物相容性PLK1抑制剂，IC50为2 nM，具有抗肿瘤活性，对PLK2和PLK3无活性。
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Desonide是非氟化皮质类固醇抗炎剂，能作用于糖皮质激素受体。
More
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Hydrocortisone (氢化可的松) 为主要的糖皮质素，由肾上腺皮质分泌。
More
-
Dexamethasone (DEX), a synthetic glucocorticoid, is widely used in clinical settings for its anti-inflammatory effect. Dexamethasone (DHAP)是一种抗炎剂和免疫抑制剂。
More
-
Prednisolone是糖皮质素。
More
-
NMS-1286937是选择性的口服生物相容性PLK1抑制剂，IC50为2 nM，具有抗肿瘤活性，对PLK2和PLK3无活性。
More
-
Desonide是非氟化皮质类固醇抗炎剂，能作用于糖皮质激素受体。
More
