VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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INH1是Hec1 抑制剂 INH1 also causes arrest of mitosis。
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Iloprost是Prostacyclin (PGI2) 的类似物。
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PD173074是一种有效的FGFR1抑制剂，IC50约为25 nM，也能抑制VEGFR2，IC50为100-200 nM，作用于FGFR1比作用于PDGFR和c-Src选择性高1000倍左右。
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Dovitinib是多靶点RTK抑制剂，对FLT3和c-Kit的IC50分别为1 nM和2 nM，对FGFR1/3和VEGFR1-4的IC50为8-13 nM，对InsR，EGFR，c-Met，EphA2，Tie2和Dovitinib(CHIR-258; TKI258)是多靶点RTK抑制剂，对FLT3和c-Kit的IC50分别为1 nM和2 nM，对FGFR1/3和VEGFR1-4的IC50为8-13 nM，对InsR，EGFR，c-Met，EphA2，Tie2和IGFR抑制性较弱。
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Cyclophosphamide monohydrate是一种氮芥类烷化剂，使烷基连接到DNA的鸟嘌呤碱基。
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