NBC


The sodium bicarbonate cotransporter (NBC) family is a part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. 
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    Celastrol is a potent antioxidant and anti-inflammatory agent and a novel HSP90 inhibitor.

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    Bortezomib (PS-341)是一种有效的蛋白酶抑制剂,Ki为0.6 nM。

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  • Ixazomib EY1186

    MLN2238抑制20S proteasome(20S蛋白酶体)的糜蛋白酶样蛋白水解位点(β5),IC50和Ki分别为3.4 nM和0.93 nM,也抑制caspase样(β1)和胰蛋白酶样(β2)蛋白水解位点, IC50分别为31和3500 nM。

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  • ONX-0914 EY1164

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