GABA Receptor


GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. GABA receptors influence cognition by coordinating with glutamatergic processes. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels; whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors. A subclass of ionotropic GABA receptors, insensitive to typical allosteric modulators of GABAA receptor channels such as benzodiazepines and barbiturates, designated GABAС receptor.
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    Atorvastatin calcium, a hydrophilic inhibitor, inhibits the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Atorvastatin hemicalcium salt 是高活性HMG-CoA还原酶抑制剂,IC50为8 nM。

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    Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines.

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    Flumazenil(Ro 15-1788)是非选择性含α1,α2,α3和α5 GABAA受体拮抗剂。

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    EUK 134是一种合成的超氧化物歧化酶(SOD)/过氧化氢酶类似物,具有强效的抗氧化活性,且抑制β-amyloid(β-淀粉样蛋白)和相关的淀粉样纤维形成。

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  • Mevastatin EY1349

    Mevastatin (Compactin; ML236B)抑制HMG-CoA还原酶(HMGCR),可抑制类异戊二烯的生物合成,阻断蛋白的异戊二烯化,降低血浆胆固醇水平。

    More
  • Atorvastatin Calcium EY0274

    Atorvastatin calcium, a hydrophilic inhibitor, inhibits the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Atorvastatin hemicalcium salt 是高活性HMG-CoA还原酶抑制剂,IC50为8 nM。

    More
  • Naringenin EY1651

    Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines.

    More
  • Flumazenil EY1568

    Flumazenil(Ro 15-1788)是非选择性含α1,α2,α3和α5 GABAA受体拮抗剂。

    More
  • EUK 134 EY1456

    EUK 134是一种合成的超氧化物歧化酶(SOD)/过氧化氢酶类似物,具有强效的抗氧化活性,且抑制β-amyloid(β-淀粉样蛋白)和相关的淀粉样纤维形成。

    More
  • Mevastatin EY1349

    Mevastatin (Compactin; ML236B)抑制HMG-CoA还原酶(HMGCR),可抑制类异戊二烯的生物合成,阻断蛋白的异戊二烯化,降低血浆胆固醇水平。

    More
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