EAATs(Glutamate transporters)
EAATs (Glutamate transporters, Excitatory amino-acid transporters,SLC1, GLT-1), being the most abundant subtype of glutamate transporter in the CNS, is a protein thatplays a key role in regulation of glutamate neurotransmission. and are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia), EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).
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Hydroxyurea具有抗肿瘤活性，能通过抑制核苷二磷酸还原酶来阻断DNA合成。
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Puromycin 2HCl 是一种氨基核苷抗菌素，其可作为蛋白质合成的抑制剂。
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Gemcitabine (吉西他滨; LY-188011; NSC 613327) 是DNA合成抑制剂，对PANC1，MIAPaCa2，BxPC3和Capan2细胞的IC50分别为50 nM，40 nM，18 nM和12 nM。
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Bleomycin Sulfate是一种糖肽类抗生素，作用于UT-SCC-19A细胞，IC50为4 nM。
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Cytarabine (阿糖胞苷; AraC)具有抗代谢和抗DNA合成活性。
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