Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
MoreSivelestat sodium tetrahydrate是人源白细胞弹性蛋白酶(neutrophil elastase)竞争性抑制剂,IC50值为44nM。
MoreLidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.
MoreEtonogestrel is a biologically active metabolite of Desogestrel. The compound is a steroidal progestin.
MoreHydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid.
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