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Dehydrogenase


Dehydrogenase is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by a reduction reaction that removes one or more hydrogens from a substrate to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.

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    Gimeracil是二氢嘧啶脱氢酶（DPYD）抑制剂，能降解血液中的包含5-fluorouracil等的嘧啶。

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  • Glycyrrhizin EY1285

    Glycyrrhizic acid is a widely used anti-inflammatory agent isolated from the licorice root.

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  • MK-8245 EY1125

    MK-8245是一种靶向作用于肝脏的stearoyl-CoA desaturase (SCD)（硬脂酰辅酶A去饱和酶）抑制剂，作用于人类SCD1时，IC50为1 nM，作用于大鼠和小鼠SCD1时，IC50为3 nM，具有抗糖尿病和抗高脂血症作用。

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  • Emodin EY1103

    Emodin是存在于多种植物根和树皮中的天然蒽醌，可通过调节不同的信号通路展现抗肿瘤细胞增殖的活性。

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  • Gossypol EY1045

    Gossypol具有抗癌，抗炎活性，能结合Bcl-2。

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