NMDAR
NMDAR(N-methyl-D-aspartate receptor) is a glutamate receptor and ion channel protein found in nerve cells. It is activated when glutamate and glycine (or D-serine) bind to it, and when activated it allows positively charged ions to flow through the cell membrane. The NMDA receptor is very important for controlling synaptic plasticity and memory function. The NMDAR is a specific type of ionotropic glutamate receptor.
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L-Aspartic acid是NMDA 激动剂。
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L-701,252是NMDA 拮抗剂, 作用于甘氨酸位点 (glycine site)。
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L-701,324是NMDA 拮抗剂, 作用于甘氨酸位点 (glycine site)。
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Ketamine hydrochloride是非竞争性 NMDA 受体拮抗剂。
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Ifenprodil hemitartrate是非竞争性 NMDA 拮抗剂。 也是 σ 的配体。
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