Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Pimobendan EY2253

    Pimobendan is a selective inhibitor of phosphodiesterase III(PDE3) with IC50 of 0.32 μM. Pimobendan is an inotropic agent with a dual mechanism of action: it increases myocardial contractility by increasing calcium sensitization to troponin C and it promotes vasodilatio.

    More

  • Apixaban EY2254

    Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively.

    More

  • Cefdinir EY2255

    Cefdinir(Omnicef) is a cephalosporin and bacteriocidal antibiotic.

    More

  • Doripenem Hydrate EY2239

    Doripenem Hydrate is an ultra-broad spectrum injectable antibiotic.

    More

  • Marbofloxacin EY2246

    Marbofloxacin is a potent antibiotic of which depends upon its inhibition of DNA-gyrase. Marbofloxacin is a synthetic, broad spectrum bactericidal agent which is a fluorinated carboxylic acid derivative third generatino quinolone antibacterial.

    More
    • Current page62, Total Pages360, Total Record1796 First Prev 6061626364 Next Last Goto
More