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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • ICI 162，846 EI1328

    ICI 162，846是活性的 H2 拮抗剂， 体内有效。

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  • ICI 204，448 hydrochloride EI1330

    ICI 204，448 hydrochloride是κ 激动剂， 作用于外周（acts peripherally）。

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  • HX 531 EI1314

    HX 531是活性的 RXR 拮抗剂。

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  • HX 630 EI1315

    HX 630是RXR synergist。

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  • Ibotenic acid EI1319

    Ibotenic acid是非选择性 NMDA 激动剂。

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