In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
HX 531是活性的 RXR 拮抗剂。
MoreHX 630是RXR synergist。
MoreIbotenic acid是非选择性 NMDA 激动剂。
MoreIbudilast是PDE 抑制剂 (非选择性)。
MoreHomoquinolinic acid是选择性, 活性的 NMDA 激动剂。
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