Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Marbofloxacin EY2246

    Marbofloxacin is a potent antibiotic of which depends upon its inhibition of DNA-gyrase. Marbofloxacin is a synthetic, broad spectrum bactericidal agent which is a fluorinated carboxylic acid derivative third generatino quinolone antibacterial.

    More

  • Felbamate EY2237

    Felbamate (Felbatol,FBM) is an anticonvulsant drug used in the treatment of epilepsy.

    More

  • Acitretin EY2238

    Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis. Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs). Acitretin is a second generation retinoid used for psoriasis.

    More

  • Artemisinin EY2231

    Artemisinin, a potent antimalarial, can be used to cure multidrug-resistant Plasmodium falciparum infections.

    More

  • Masitinib EY2221

    Masitinib, a novel phenylaminothiazole-type derivative, is an inhibitor of the class III receptor tyrosine kinase stem-cell growth factor receptor (c-Kit) with IC50 of 200 nM, platelet-derived growth factor receptor α and β and the non-receptor tyrosine kinase Lyn(PDGFRα/β with IC50 of 540 nM/800 nM).

    More
    • Current page55, Total Pages352, Total Record1757 First Prev 5354555657 Next Last Goto
More