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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Olsalazine Sodium is a anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.

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    Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.

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  • Ampiroxicam EY2472

    Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

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  • Hyoscyamine EY2473

    Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.

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  • Homatropine Methylbromide EY2476

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