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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments. Triclosan is an inhibitor of fatty acid synthase which has demonstrated bacteriostatic, antiseptic, and preservative properties.

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  • Trihexyphenidyl hydrochloride EY2656

    Trihexyphenidyl hydrochloride is an antiparkinsonian agent of the antimuscarinic class. Trihexyphenidyl hydrochloride is an antiparkinsonian agent of the antimuscarinic class, binds to the M1 muscarinic receptor.

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    Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners. Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity.

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  • Bithionol EY2662

    Bithionol is a potent inhibitor of soluble adenylyl cyclase(sAC) and has antibacterial and anthelmintic properties along with algaecide activity. Bithionol is a clinically approved anti-parasitic drug; has been shown to inhibit solid tumor growth in several preclinical cancer models.

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  • Bronopol EY2663

    Bronopol(2-bromo-2-nitropropane-1,3-diol) is antibacterial agent, used as preservative in cosmetic industry. Bronopol is an antimicrobial, with low mammalian toxicity (at in-use levels) and high activity against bacteria (especially the troublesome Gram-negative species).

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