Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
-
Medetomidine hydrochloride是α2肾上腺素受体激动剂，对α2和α1肾上腺素受体的Ki分别为1.08 nM和1750 nM。
More
-
Epinephrine hydrochloride is a hormone and a neurotransmitter.
More
-
Dexmedetomidine是特护病房和麻醉师使用的一种镇静剂。
More
-
Mirtazapine是抗抑郁的5-HT受体抑制剂。
More
-
在兔肺β1-肾上腺素受体结合实验中，Nebivolol 选择性阻断β1受体，IC50为0.8 nM。
More
-
Medetomidine hydrochloride是α2肾上腺素受体激动剂，对α2和α1肾上腺素受体的Ki分别为1.08 nM和1750 nM。
More
-
Epinephrine hydrochloride is a hormone and a neurotransmitter.
More
-
Dexmedetomidine是特护病房和麻醉师使用的一种镇静剂。
More
-
Mirtazapine是抗抑郁的5-HT受体抑制剂。
More
-
在兔肺β1-肾上腺素受体结合实验中，Nebivolol 选择性阻断β1受体，IC50为0.8 nM。
More
