Sodium Channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("Voltage-gated", "voltage-sensitive", or "voltage-dependent" sodium channel also called "VGSCs" or "Nav channel") or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials.
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Immepip dihydrobromide是标准H3 激动剂。 也是H4的激动剂。
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Immethridine dihydrobromide是活性的 H3 激动剂(highly selective over H4)。
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Phenytoin Sodium is a sodium channel protein inhibitor. Phenytoin Sodium stabilizes excitable membranes the its effects on sodium, potassium and calcium channels.
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Amiloride hydrochloride (盐酸阿米洛利) 是表皮钠离子通道阻断剂。
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Bupivacaine hydrochloride (盐酸布比卡因) 是局麻化合物。
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