SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
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CHPG是mGlu5 选择性激动剂。
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CDPPB是mGlu5阳性变构调节剂 。
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CBiPES hydrochloride是mGlu2阳性变构调节剂。
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Bay 36-7620是非竞争性 mGlu1 拮抗剂有反向激动剂活性。
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AZD 9272是活性的，选择性 mGlu5 拮抗剂， 可透过血脑屏障。
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CHPG是mGlu5 选择性激动剂。
More
-
CDPPB是mGlu5阳性变构调节剂 。
More
-
CBiPES hydrochloride是mGlu2阳性变构调节剂。
More
-
Bay 36-7620是非竞争性 mGlu1 拮抗剂有反向激动剂活性。
More
-
AZD 9272是活性的，选择性 mGlu5 拮抗剂， 可透过血脑屏障。
More
-
CHPG是mGlu5 选择性激动剂。
More
-
CDPPB是mGlu5阳性变构调节剂 。
More
-
CBiPES hydrochloride是mGlu2阳性变构调节剂。
More
-
Bay 36-7620是非竞争性 mGlu1 拮抗剂有反向激动剂活性。
More
-
AZD 9272是活性的，选择性 mGlu5 拮抗剂， 可透过血脑屏障。
More
