SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
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S-Sulfo-L-cysteine sodium salt是Group I 激动剂。
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SR 140333是活性的 NK1 受体拮抗剂。
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Spaglumic acid是选择性mGlu3激动剂。
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SIB 1893是mGlu5的拮抗剂，mGlu4的阳性变构的调节剂（positive allosteric modulator）。
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SIB 1757是高选择性mGlu5拮抗剂。
More
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S-Sulfo-L-cysteine sodium salt是Group I 激动剂。
More
-
SR 140333是活性的 NK1 受体拮抗剂。
More
-
Spaglumic acid是选择性mGlu3激动剂。
More
-
SIB 1893是mGlu5的拮抗剂，mGlu4的阳性变构的调节剂（positive allosteric modulator）。
More
-
SIB 1757是高选择性mGlu5拮抗剂。
More
-
S-Sulfo-L-cysteine sodium salt是Group I 激动剂。
More
-
SR 140333是活性的 NK1 受体拮抗剂。
More
-
Spaglumic acid是选择性mGlu3激动剂。
More
-
SIB 1893是mGlu5的拮抗剂，mGlu4的阳性变构的调节剂（positive allosteric modulator）。
More
-
SIB 1757是高选择性mGlu5拮抗剂。
More
