P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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    Ulipristal是一种选择性的孕酮受体调节剂(SPRM),用于无保护措施性交或避孕失败后的紧急避孕。

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  • Ulipristal EY0414

    Ulipristal是一种选择性的孕酮受体调节剂(SPRM),用于无保护措施性交或避孕失败后的紧急避孕。

    More
  • Estradiol Benzoate EY0401

    Estradiol Benzoate是一种雌激素类似物,可以与人源,鼠源以及鸡的ERα结合,IC50范围22-28 nM。

    More
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