P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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Ocinaplon是GABAA 调节剂，抗焦虑剂。
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NNC 711是GAT-1选择性抑制剂。
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NNC 05-2090 hydrochloride是GABA uptake inhibitor（摄取抑制剂)，具有适当的 BGT-1 选择性。
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Muscimol是活性的 GABAA 激动剂。
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MRK 016是α5选择性的GABAA反向激动剂。
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Ocinaplon是GABAA 调节剂，抗焦虑剂。
More
-
NNC 711是GAT-1选择性抑制剂。
More
-
NNC 05-2090 hydrochloride是GABA uptake inhibitor（摄取抑制剂)，具有适当的 BGT-1 选择性。
More
-
Muscimol是活性的 GABAA 激动剂。
More
-
MRK 016是α5选择性的GABAA反向激动剂。
More
