P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
  • Zearalenone EI2995

    Zearalenone是Estrogen receptor(ER)的配体。

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  • Vigabatrin EI2883

    Vigabatrin是GABA-T 抑制剂。

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  • U 89843A EI2832

    U 89843A是U 89843A is a positive allosteric modulator of GABAA receptors.。

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  • U 90042 EI2833

    U 90042是GABAA 受体的配体。

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  • U 93631 EI2834

    U 93631是GABAA 受体的拮抗剂。

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  • Zearalenone EI2995

    Zearalenone是Estrogen receptor(ER)的配体。

    More
  • Vigabatrin EI2883

    Vigabatrin是GABA-T 抑制剂。

    More
  • U 89843A EI2832

    U 89843A是U 89843A is a positive allosteric modulator of GABAA receptors.。

    More
  • U 90042 EI2833

    U 90042是GABAA 受体的配体。

    More
  • U 93631 EI2834

    U 93631是GABAA 受体的拮抗剂。

    More
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