Oct-4


Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
  • Fluorobexarotene EI1129

    Fluorobexarotene是RXR 激动剂。

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  • Fenoldopam hydrochloride EI1112

    Fenoldopam hydrochloride是选择性 D1样部分激动剂。

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  • Fananserin EI1108

    Fananserin是5-HT2A 拮抗剂。 也是D4 拮抗剂。

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  • Eticlopride hydrochloride EI1101

    Eticlopride hydrochloride是选择性 D2/D3 拮抗剂。

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  • Domperidone EI1025

    Domperidone是外周D2样受体拮抗剂(peripheral D2-like)。

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  • Fluorobexarotene EI1129

    Fluorobexarotene是RXR 激动剂。

    More
  • Fenoldopam hydrochloride EI1112

    Fenoldopam hydrochloride是选择性 D1样部分激动剂。

    More
  • Fananserin EI1108

    Fananserin是5-HT2A 拮抗剂。 也是D4 拮抗剂。

    More
  • Eticlopride hydrochloride EI1101

    Eticlopride hydrochloride是选择性 D2/D3 拮抗剂。

    More
  • Domperidone EI1025

    Domperidone是外周D2样受体拮抗剂(peripheral D2-like)。

    More
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