Oct-4
Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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LE 300是活性的，选择性 dopamine D1 拮抗剂。
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L-741，742 hydrochloride是高选择性 D4 拮抗剂。
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L-745，870 trihydrochloride是高选择性 D4 拮抗剂。
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JHW 007 hydrochloride是高亲和性 dopamine uptake inhibitor（摄取抑制剂）。
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Indatraline hydrochloride是活性的 5-HT uptake inhibitor（摄取抑制剂）， 也抑制 dopamine，noradrenalin的吸收。
More
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LE 300是活性的，选择性 dopamine D1 拮抗剂。
More
-
L-741，742 hydrochloride是高选择性 D4 拮抗剂。
More
-
L-745，870 trihydrochloride是高选择性 D4 拮抗剂。
More
-
JHW 007 hydrochloride是高亲和性 dopamine uptake inhibitor（摄取抑制剂）。
More
-
Indatraline hydrochloride是活性的 5-HT uptake inhibitor（摄取抑制剂）， 也抑制 dopamine，noradrenalin的吸收。
More
