NMDA
NMDA (N-Methyl-D-aspartic acid or N-Methyl-D-aspartate) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors. NMDA is an excitotoxin,this trait has applications in behavioral neuroscience research.
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KRCA 0008是活性的 Ack1,ALK dual 抑制剂, 口服有效。
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Ketamine hydrochloride是非竞争性 NMDA 受体拮抗剂。
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IRL-2500是活性的 ETB 拮抗剂。
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Ifenprodil hemitartrate是非竞争性 NMDA 拮抗剂。 也是 σ 的配体。
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Bosentan 是一种 endothelin (ET) receptor 拮抗剂,其作用于 ET-A 和 ET-B 的 Ki 分别为 4.7 nM 和 95 nM。
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