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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

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    Haloperidol hydrochloride是拮抗剂, 部分 D2 选择性。

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  • GSK 789472 hydrochloride EI1247

    GSK 789472 hydrochloride是D3 拮抗剂。 也是D2部分激动剂。

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  • GR 103691 EI1213

    GR 103691是高选择性 D3 拮抗剂。

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  • GBR 13069 dihydrochloride EI1176

    GBR 13069 dihydrochloride是活性的 dopamine uptake inhibitor(摄取抑制剂)。

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  • GBR 12935 dihydrochloride EI1175

    GBR 12935 dihydrochloride是选择性 dopamine uptake inhibitor(摄取抑制剂)。

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